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The structures of serotonin and related compounds are shown in figure 13 1.
Serotonin structure. More specifically however serotonin is a monoamine neurotransmitter ie a neurotransmitter. The findings provide insights for designing new ways to target the transporter for more effective medications. Serotonin is found mostly in the digestive system although its also in blood platelets and throughout the. The combination of the hydroxyl group in the 5 position of the indole nucleus and a primary amine nitrogen serving as a proton acceptor at physiological ph makes 5 hta hydrophilic substance.
The carbon atoms in the chemical structure of serotonin are implied to be located at the corner s and hydrogen atoms attached to carbon atoms are not indicated each carbon atom is considered to be associated with enough hydrogen atoms to provide the carbon atom with four bonds. Serotonin is a chemical your body produces thats needed for your nerve cells and brain to function. Serotonin is a primary amino compound that is the 5 hydroxy derivative of tryptamineit has a role as a human metabolite a mouse metabolite and a neurotransmitter. Serotonin s r e t o n n s er e or 5 hydroxytryptamine 5 ht is a monoamine neurotransmitterits biological function is complex and multifaceted modulating mood cognition reward learning memory and numerous physiological processes such as vomiting and vasoconstriction.
Slice through the human serotonin transporter structure illustrating the ssri binding sites. Structure properties spectra suppliers and links for. It derives from a tryptamineit is a conjugate base of a serotonin1. Severe serotonin syndrome can cause death if not treated.
But too much serotonin causes signs and symptoms that can range from mild shivering and diarrhea to severe muscle rigidity fever and seizures. Serotonin hydrochloride c10h13cln2o cid 160436 structure chemical names physical and chemical properties classification patents literature biological. It is a monoamine molecular messenger a primary amino compound a member of phenols a member of hydroxyindoles and a member of tryptamines. Researchers determined the 3 d structure of the serotonin transporter and visualized how 2 common antidepressants interact with the protein.
This means that serotonin is a chemical substance synthesized in the brain that performs a large number of activities in the central nervous system. It sends signals between your nerve cells.
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